Réaction #1121771

Équation de réaction

3-tert-butyldimethylsilyloxybenzoic acid

thionyl chloride

→

3-tert-Butyldimethylsilyloxybenzoyl chloride

Conditions de réaction

Traitement

1. 1
   Températurewas heated
2. 2
   Températureat reflux for 90 mins
3. 3
   ConcentrationThe reaction mixture was concentrated under reduced pressure
4. 4
   Autreto give an oil
5. 5
   Autreyield 5.77 parts of the following structure

Mode opératoire

Into a 100 mL round bottom flask a mixture of 5 parts of 3-tert-butyldimethylsilyloxybenzoic acid and 25 mL of thionyl chloride was heated at reflux for 90 mins. The reaction mixture was concentrated under reduced pressure to give an oil, yield 5.77 parts of the following structure.

Source