Réaction #11077

Équation de réaction

intermediate 19b

3-benzyloxycarbonylamino-6-methyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid

intermediate 22a

3-benzyloxycarbonylamino-6-ethyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid tert-butyl ester

→

intermediate 22b

Rendement 99.0%

3-benzyloxycarbonylamino-6-ethyl-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrimidine-6-carboxylic acid

Rendement 99.0%

Conditions de réaction

Mode opératoire

According to the procedure for the preparation of intermediate 19b, intermediate 22a (41 mg, 413.47 mmol) was deprotected to afford 35 mg (99%) of intermediate 22b. MS (ESI) 358.3 (M+H+), 356.2 (M−H+).

Source