Réaction #10896

Équation de réaction

cyanamide

1-(4-isothiocyanatophenyl)-4-methylpiperazine

1-(1,3-benzodioxol-5-yl)-2-bromoethanone

1-(1,3-Benzodioxol-5-yl)-2-bromoethanone

→

[4-Amino-2-[[4-(4-methyl-1-piperazi nyl)phenyl]amino]-5-thiazolyl](1,3-benzodioxol-5-yl)methanone

Rendement 75.0%

Conditions de réaction

Mode opératoire

This compound was prepared in 75% yield from cyanamide (Aldrich), 1-(4-isothiocyanatophenyl)-4-methylpiperazine (of Example 1), and 1-(1,3-benzodioxol-5-yl)-2-bromoethanone (of Example 11) following the procedure used to in Example 24.

Source