Réaction #1046

Équation de réaction

di-t-butylphosphonate

di-t-butyl 2,3,3-trifluoro-2-propenylphosphonate

HCl

→

2,3,3-trifluoro-2-propenylphosphonic acid

Rendement 45.8%

Solvants

methanol

Conditions de réaction

Traitement

1. 1
   ConcentrationThe solution was concentrated
2. 2
   workup.DISSOLUTIONthe residue was redissolved in 10 mL of water
3. 3
   Lavagewashed with 10 mL of ether
4. 4
   AutreEvaporation of the aqueous layer

Mode opératoire

The above di-t-butylphosphonate (0.5 g) was dissolved in 3 mL of methanol and treated with 0.5 mL, of 3N HCl and allowed to stand at r.t. for 30 min. The solution was concentrated and the residue was redissolved in 10 mL of water and washed with 10 mL of ether. Evaporation of the aqueous layer gave 0.14 g of 2,3,3-trifluoro-2-propenylphosphonic acid as a yellow oil.

Source