Réaction #1036

Équation de réaction

1-chloro-1,2-dibromotrifluoroethane

1,1,2-trichlorotrifiuoroethane

vinylidene chloride

persulfate sodium formate

→

4-bromo-3-chloro-3,4,4-trifiuorobutanoic acid

3,4- dichloro-3,4,4-trifluorobutanoic acid

Solvants

DMF

Conditions de réaction

Mode opératoire

A one pot reaction of 1-chloro-1,2-dibromotrifluoroethane (VI) or 1,1,2-trichlorotrifiuoroethane (X) with vinylidene chloride in the presence of ammoninm persulfate/sodium formate/air in DMF to give 4-bromo-3-chloro-3,4,4-trifiuorobutanoic acid (VIII) or 3,4- dichloro-3,4,4-trifluorobutanoic acid (XI).

Source