Recherche de Sous-structure

93810

Cc1cc(C)c(CNC(=O)c2cc(Br)cc3c2ccn3C(C)C)c(=O)[nH]1
Reaction #70678
6-bromo-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(1-methylethyl)-1H-indole-4-carboxamide
Rendement 74.4%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(N4CCN(C)CC4)nc3)cc3c2ccn3C(C)C)c(=O)[nH]1
Reaction #70679
N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide
Rendement 75.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #70680
solid
Rendement 50.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #70681
solid
Rendement 41.0%DOI: 10.6084/m9.figshare.5104873.v1
CCC(C)n1cc(C)c2c(C(=O)NCc3c(C)cc(C)[nH]c3=O)cc(Br)cc21
Reaction #70682
6-bromo-1-(sec-butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-1H-indole-4-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1
CCC(C)n1cc(C)c2c(C(=O)NCc3c(C)cc(C)[nH]c3=O)cc(-c3ccc(N4CCNCC4)nc3)cc21
Reaction #70683
1-(sec-butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1
CC[C@H](C)n1cc(C)c2c(C(=O)NCc3c(C)cc(C)[nH]c3=O)cc(-c3ccc(N4CCNCC4)nc3)cc21
Reaction #70684
product
Rendement 76.8%DOI: 10.6084/m9.figshare.5104873.v1
CC[C@@H](C)n1cc(C)c2c(C(=O)NCc3c(C)cc(C)[nH]c3=O)cc(-c3ccc(N4CCNCC4)nc3)cc21
Reaction #70685
product
Rendement 75.9%DOI: 10.6084/m9.figshare.5104873.v1
CCC(C)n1cc(C)c2c(C(=O)NCc3c(C)cc(C)[nH]c3=O)cc(-c3cccc(CN(C)C)c3)cc21
Reaction #70686
1-(sec-Butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-6-(3-((dimethylamino)methyl)phenyl)-3-methyl-1H-indole-4-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1
CC[C@H](C)n1cc(C)c2c(C(=O)NCc3c(C)cc(C)[nH]c3=O)cc(-c3cccc(CN(C)C)c3)cc21
Reaction #70687
6-{3-[(Dimethylamino)methyl]phenyl}-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-1H-indole-4-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1
CC[C@@H](C)n1cc(C)c2c(C(=O)NCc3c(C)cc(C)[nH]c3=O)cc(-c3cccc(CN(C)C)c3)cc21
Reaction #70688
6-{3-[(dimethylamino)methyl]phenyl}-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-methyl-1-[(1R)-1-methylpropyl]-1H-indole-4-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(N4CCNCC4)nc3)cc3c2c(C)cn3C2CCCC2)c(=O)[nH]1
Reaction #70689
product
Rendement 76.4%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(C)c(CNC(=O)c2cccc3c2ccn3C(C)C)c(=O)[nH]1
Reaction #70692
N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(1-methylethyl)-1H-indole-4-carboxamide
Rendement 60.2%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(C)c(CNC(=O)c2cc(S(C)(=O)=O)cc3c2c(C)cn3C2CC2)c(=O)[nH]1
Reaction #70693
1-cyclopropyl-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-methyl-6-(methylsulfonyl)-1H-indole-4-carboxamide
Rendement 79.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(CO)[nH]c(=O)c1CNC(=O)c1cc(Br)cc2c1c(C)cn2C(C)C
Reaction #70713
6-bromo-N-((6-(hydroxymethyl)-4-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-1H-indole-4-carboxamide
Rendement 39.0%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(CN)[nH]c(=O)c1CNC(=O)c1cc(Br)cc2c1c(C)cn2C(C)C
Reaction #70715
N-((6-(aminomethyl)-4-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-6-bromo-1-isopropyl-3-methyl-1H-indole-4-carboxamide
Rendement 82.3%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(C)c(CNC(=O)c2cc(Br)cc3c2ccn3C(C)C)c(=O)[nH]1
Reaction #90576
6-bromo-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(1-methylethyl)-1H-indole-4-carboxamide
Rendement 74.4%DOI: 10.6084/m9.figshare.5104873.v1
Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(N4CCN(C)CC4)nc3)cc3c2ccn3C(C)C)c(=O)[nH]1
Reaction #90577
N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide
Rendement 75.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #90578
solid
Rendement 50.0%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #90579
solid
Rendement 41.0%DOI: 10.6084/m9.figshare.5104873.v1
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