Impliqué dans 4 réactions

458414

CC(C)(C)[Si](C)(C)OC[C@H](c1ccc(Cl)c(F)c1)n1ccc(-c2ccnc(NC3CC4CC3CO4)n2)cc1=O
Reaction #1861399
4-(2-(2-oxabicyclo[2.2.1]heptan-5-ylamino)pyrimidin-4-yl)-1-((S)-2-(tert-butyldimethylsilyloxy)-1-(4-chloro-3-fluorophenyl)ethyl)pyridin-2(1H)-one
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_02
O=c1cc(-c2ccnc(NC3CC4CC3CO4)n2)ccn1[C@H](CO)c1ccc(Cl)c(F)c1
Reaction #1861400
4-(2-(2-oxabicyclo[2.2.1]heptan-5-ylamino)pyrimidin-4-yl)-1-((S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)pyridin-2(1H)-one
Rendement 29.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_02
CC(C)(C)[Si](C)(C)OC[C@H](c1ccc(Cl)c(F)c1)n1ccc(-c2ccnc(NC3CC4CC3CO4)n2)cc1=O
Reaction #2453045
4-(2-(2-oxabicyclo[2.2.1]heptan-5-ylamino)pyrimidin-4-yl)-1-((S)-2-(tert-butyldimethylsilyloxy)-1-(4-chloro-3-fluorophenyl)ethyl)pyridin-2(1H)-one
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_04
O=c1cc(-c2ccnc(NC3CC4CC3CO4)n2)ccn1[C@H](CO)c1ccc(Cl)c(F)c1
Reaction #2453046
4-(2-(2-oxabicyclo[2.2.1]heptan-5-ylamino)pyrimidin-4-yl)-1-((S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)pyridin-2(1H)-one
Rendement 29.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_04