Recherche de Sous-structure

340139

COc1cccc(OC2=CC(=O)N([C@@H](CC(C)C)C(=O)Nc3ccn(CC(C)(C)O)n3)C2)c1Cl

Reaction #47261

(S)-2-[4-(2-Chloro-3-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

Rendement 71.0%DOI: 10.6084/m9.figshare.5104873.v1

COc1cccc(OC2=CC(=O)N(C(CC3CCOCC3)C(=O)Nc3ccn(CC(C)(C)O)n3)C2)c1Cl

Reaction #47264

2-[4-(2-chloro-3-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-3-(tetrahydro-pyran-4-yl)-propionamide

Rendement 62.0%DOI: 10.6084/m9.figshare.5104873.v1

COc1cccc(OC2=CC(=O)N([C@@H](CC3CCCC3)C(=O)Nc3ccn(CC(C)(C)O)n3)C2)c1Cl

Reaction #47265

(S)-2-[4-(2-chloro-3-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-3-cyclopentyl-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-propionamide

Rendement 54.0%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCCC2)N2CC(Oc3c(F)cccc3Cl)=CC2=O)n1

Reaction #47283

(S)-2-[4-(2-chloro-6-fluoro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-3-cyclohexyl-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-propionamide

Rendement 41.0%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)C[C@@H](C(=O)Nc1ccn(CC(C)(C)O)n1)N1CC(Oc2cccc(Cl)c2Cl)=CC1=O

Reaction #47292

(S)-2-[4-(2,3-dichloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

DOI: 10.6084/m9.figshare.5104873.v1

CC(C)C[C@@H](C(=O)Nc1ccn(C)n1)N1CC(Oc2cccc(Cl)c2Cl)=CC1=O

Reaction #47293

(S)-2-[4-(2,3-dichloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid (1-methyl-1H-pyrazol-3-yl)-amide

DOI: 10.6084/m9.figshare.5104873.v1

CC(C)(O)Cn1ccc(NC(=O)[C@H](CC2CCCCO2)N2CC(Oc3cccc(Cl)c3Cl)=CC2=O)n1

Reaction #47312

(S)-2-[4-(2,3-dichloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-N-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-3-(tetrahydro-pyran-2-yl)-propionamide

Rendement 3.7%DOI: 10.6084/m9.figshare.5104873.v1

CCOC(=O)C=C(CN[C@@H](C[C@@H](C)OCC)C(=O)Nc1ccn(CC(C)(C)O)n1)Oc1cccc(Cl)c1Cl

Reaction #47318

3-(2,3-dichloro-phenoxy)-4-{(1S,3R)-3-ethoxy-1-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-ylcarbamoyl]-butylamino}-but-2-enoic acid ethyl ester

DOI: 10.6084/m9.figshare.5104873.v1

CCOC(=O)C=C(CN[C@@H](C[C@H](C)OCC)C(=O)Nc1ccn(CC(C)(C)O)n1)Oc1cccc(Cl)c1Cl

Reaction #47323

3-(2,3-dichloro-phenoxy)-4-{(1S,3S)-3-ethoxy-1-[1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-ylcarbamoyl]-butylamino}-but-2-enoic acid ethyl ester

DOI: 10.6084/m9.figshare.5104873.v1

COCCc1nsc(NC(=O)[C@H](CC(C)C)N2CC(Oc3ccccc3Cl)=CC2=O)n1

Reaction #47374

(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [3-(2-methoxy-ethyl)-[1,2,4]thiadiazol-5-yl]-amide

Rendement 28.1%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)C[C@@H](C(=O)Nc1nc(C2CC2)ns1)N1CC(Oc2ccccc2Cl)=CC1=O

Reaction #47375

(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid (3-cyclopropyl-[1,2,4]thiadiazol-5-yl)-amide

Rendement 32.4%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)C[C@@H](C(=O)Nc1nc(CCC(F)(F)F)ns1)N1CC(Oc2ccccc2Cl)=CC1=O

Reaction #47377

(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [3-(3,3,3-trifluoro-propyl)-[1,2,4]thiadiazol-5-yl]-amide

Rendement 49.2%DOI: 10.6084/m9.figshare.5104873.v1

Cc1nsc(NC(=O)[C@H](CC(C)C)N2CC(Oc3ccccc3Cl)=CC2=O)n1

Reaction #47378

(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid (3-methyl-[1,2,4]thiadiazol-5-yl)-amide

Rendement 43.0%DOI: 10.6084/m9.figshare.5104873.v1

CC(C)C[C@@H](C(=O)Nc1nc(N(C)C)ns1)N1CC(Oc2ccccc2Cl)=CC1=O

Reaction #47379

(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid (3-dimethylamino-[1,2,4]thiadiazol-5-yl)-amide

Rendement 36.0%DOI: 10.6084/m9.figshare.5104873.v1

COc1ccc(Cc2nsc(NC(=O)[C@H](CC(C)C)N3CC(Oc4ccccc4Cl)=CC3=O)n2)cc1

Reaction #47382

(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [3-(4-methoxy-benzyl)-[1,2,4]thiadiazol-5-yl]-amide

Rendement 49.0%DOI: 10.6084/m9.figshare.5104873.v1

CCc1nsc(NC(=O)[C@H](CC(C)C)N2CC(Oc3ccccc3Cl)=CC2=O)n1

Reaction #47383

(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid (3-ethyl-[1,2,4]thiadiazol-5-yl)-amide

Rendement 59.6%DOI: 10.6084/m9.figshare.5104873.v1

C=CCOC(=O)Cc1nsc(NC(=O)[C@H](CC(C)C)N2CC(Oc3ccccc3Cl)=CC2=O)n1

Reaction #47384

(5-{(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoylamino}-[1,2,4]thiadiazol-3-yl)-acetic acid allyl ester

Rendement 70.0%DOI: 10.6084/m9.figshare.5104873.v1

COCc1nsc(NC(=O)[C@H](CC(C)C)N2CC(Oc3ccccc3Cl)=CC2=O)n1

Reaction #47386

(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid (3-methoxymethyl-[1,2,4]thiadiazol-5-yl)-amide

Rendement 47.4%DOI: 10.6084/m9.figshare.5104873.v1

CC(=O)Cc1nsc(NC(=O)[C@H](CC(C)C)N2CC(Oc3ccccc3Cl)=CC2=O)n1

Reaction #47387

(S)-2-[4-(2-chloro-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-methyl-pentanoic acid [3-(2-oxo-propyl)-[1,2,4]thiadiazol-5-yl]-amide

Rendement 40.0%DOI: 10.6084/m9.figshare.5104873.v1

COc1cccc(OC2=CC(=O)N(C(CC(C)(C)F)C(=O)Nc3ccn(CC(C)(C)O)n3)C2)c1Cl

Reaction #47464

2-[4-(2-chloro-3-methoxy-phenoxy)-2-oxo-2,5-dihydro-pyrrol-1-yl]-4-fluoro-4-methyl-pentanoic acid [1-(2-hydroxy-2-methyl-propyl)-1H-pyrazol-3-yl]-amide

Rendement 57.0%DOI: 10.6084/m9.figshare.5104873.v1