Reacción #992690

ord-691bda8024df427ebdc4c7814c53ac21

Ecuación de reacción

O=C(O)CC(=O)O
Malonic acid
N=C(N)N.O=C(O)O
Guanidine carbonate
O=C=O
carbon dioxide
→
NC(N)=[NH2+].NC(N)=[NH2+].O=C([O-])CC(=O)[O-]
Bis(guanidinium) Malonate

Reactantes

O=C(O)CC(=O)O
Malonic acid
N=C(N)N.O=C(O)O
Guanidine carbonate
O=C=O
carbon dioxide

Reactivos

Ninguno

Disolventes

O
water

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroThe water was removed in vacuo
  2. 2
    Temperaturawith heating to approximately 90° C. for 4 hours
  3. 3
    OtroThe product was isolated as a white solid

Procedimiento

Malonic acid (1.00 g, 9.61 mmol) was dissolved in 30 ml of distilled water. Guanidine carbonate (1.73 g, 9.61 mmol) was added via syringe at room temperature (carbon dioxide gas was evolved) and the reaction was stirred at room temperature for 24 hours. The water was removed in vacuo with heating to approximately 90° C. for 4 hours. The product was isolated as a white solid.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08012277B2uspto-grants-2011_09