Reacción #992682

Ecuación de reacción

Trifluoroacetic acid

Guanidine carbonate

→

Guanidinium TFA

Disolventes

water

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.STIRRINGwith stirring as
2. 2
   Otroto avoid bubbling over the sides of the beaker due to the evolution of carbon dioxide
3. 3
   workup.STIRRINGThe reaction was stirred at room temperature for 2 hours
4. 4
   OtroThe water was removed in vacuo
5. 5
   OtroThe product was recovered as a white crystalline solid

Procedimiento

Trifluoroacetic acid (50.0 ml, 74.0 g, 649 mmol) was added to 500 ml of distilled water in a 4-liter beaker with stirring. Guanidine carbonate (58.5 g, 324.5 mmol) was added at room temperature in portions with stirring as to avoid bubbling over the sides of the beaker due to the evolution of carbon dioxide. The reaction was stirred at room temperature for 2 hours. The water was removed in vacuo with heating to approximately 90° C. for 4 hours. The product was recovered as a white crystalline solid.

Fuente