Reacción #979953

Ecuación de reacción

4-(4-cyanophenyl)amino-2,6-dimethyl-3-nitropyridine

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title compound

Rendimiento 94.8%

3-Amino-4(4-cyanophenyl)amino-2,6-dimethylpyridine

Rendimiento 94.8%

Disolventes

dichloromethane

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe catalyst was filtered off
2. 2
   Otrothe solvents were removed under reduced pressure

Procedimiento

A solution of 4-(4-cyanophenyl)amino-2,6-dimethyl-3-nitropyridine (5.00 g, 18.6 mmol) in a mixture of dichloromethane (20 ml) and ethanol (100 ml) was hydrogenated at 20° C. over 10% palladium on charcoal (500 mg) at 138 kPa (20 p.s.i.) for 3 hours. The catalyst was filtered off and the solvents were removed under reduced pressure to give the title compound as a brown solid (4.20 g, 94%).

Fuente