Reacción #96042

ord-8782247c338a48c8ba5cebaf3406a2ac

Ecuación de reacción

Br.COc1cc(N=C2SCC(O)(c3ccc(Cl)c(S(=O)(=O)N(C)C)c3)N2C)cc(OC)c1OC
4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-(3,4,5-trimethoxyphenyl-imino)-thiazolidin-4-ol hydrobromide
→
Br.COc1cc(N=c2scc(-c3ccc(Cl)c(S(=O)(=O)N(C)C)c3)n2C)cc(OC)c1OC
4-(4-Chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-(3,4,5-trimethoxyphenyl-imino)-4-thiazoline hydrobromide

Reactantes

Br.COc1cc(N=C2SCC(O)(c3ccc(Cl)c(S(=O)(=O)N(C)C)c3)N2C)cc(OC)c1OC
4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-(3,4,5-trimethoxyphenyl-imino)-thiazolidin-4-ol hydrobromide

Reactivos

Ninguno

Disolventes

CC(=O)O
acetic acid

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroObtained by a procedure analogous to
  2. 2
    Otroprecipitating with diisopropyl ether

Procedimiento

Obtained by a procedure analogous to that indicated in Example 1(b), from 4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-(3,4,5-trimethoxyphenyl-imino)-thiazolidin-4-ol hydrobromide, by boiling for 30 minutes in glacial acetic acid and precipitating with diisopropyl ether. Melting point 246° C.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04346088uspto-grants-1982_08