Reacción #955904

Ecuación de reacción

nitric acid

1-(1′-hydroxyoctadecyloxy)-2,3-dioctadecyloxybenzene

→

3-(1′-hydroxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene

Rendimiento 76.2%

Disolventes

dichloromethane

dichloromethane

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONDispersed
2. 2
   workup.ADDITIONwas added
3. 3
   workup.ADDITIONInto the resulting dispersion, added
4. 4
   Filtraciónsilica gel was filtered off
5. 5
   ConcentraciónAfter the filtrate was concentrated under reduced pressure, 300 ml of methanol
6. 6
   workup.ADDITIONwas added
7. 7
   workup.STIRRINGstirred
8. 8
   OtroResulting precipitant
9. 9
   Filtraciónwas filtered off

Procedimiento

Dispersed was 63 g of silica gel into 21 g of nitric acid and 150 ml of dichloromethane was added. Into the resulting dispersion, added was a solution dissolving 5.0 g of 1-(1′-hydroxyoctadecyloxy)-2,3-dioctadecyloxybenzene in 30 ml of dichloromethane. After stirring for 15 minutes, silica gel was filtered off. After the filtrate was concentrated under reduced pressure, 300 ml of methanol was added and stirred. Resulting precipitant was filtered off to obtain 4.0 g of 3-(1′-hydroxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene (yield: 76%).

Fuente