Reacción #95458

Ecuación de reacción

triethyloxonium fluoroborate

epichlorohydrin

boron trifluoride etherate

N-methyl-2-quinolone

→

Triethyloxonium fluoroborate

2-ethoxy-1-methylquinolinium fluoroborate

Rendimiento 83.5%

Disolventes

methylene chloride

ether

ether

methylene chloride

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe solid is filtered

Procedimiento

Triethyloxonium fluoroborate is prepared from 3.70 g (0.040 mole) of epichlorohydrin in 14 ml of ether and 7.58 g (0.054 mole) of boron trifluoride etherate in 6 ml of ether. The resulting solid triethyloxonium fluoroborate is dissolved in 20 ml of dry methylene chloride and treated under nitrogen with 6.47 g (0.040 mole) of N-methyl-2-quinolone in 15 ml of methylene chloride. The reaction mixture is stirred under nitrogen at room temperature overnight. The solid is filtered to give 9.2 g (83.5%) of 2-ethoxy-1-methylquinolinium fluoroborate.

Fuente