Reacción #95376

Ecuación de reacción

6,7-Bis(2,2,2-trichloroethoxycarbonyloxy)chromone-3-carboxylic acid

thionyl chloride

→

6,7-Bis(2,2,2-trichloroethoxycarbonyloxy)chromone-3-carbonyl chloride

Disolventes

benzene

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONTo the solution was added
2. 2
   TemperaturaThe mixture was refluxed
3. 3
   Concentraciónthe reaction solution was concentrated
4. 4
   workup.ADDITIONTo the concentrate was added n-hexane (5 ml)
5. 5
   Otrocrystallization of the reaction product
6. 6
   FiltraciónThe resulting product was recovered by filtration
7. 7
   Lavadowashed with n-hexan
8. 8
   Otrodried

Procedimiento

6,7-Bis(2,2,2-trichloroethoxycarbonyloxy)chromone-3-carboxylic acid (57.3 mg) was dissolved in benzene (10 ml). To the solution was added with stirring at room temperature thionyl chloride (0.5 ml). The mixture was refluxed with stirring for three hours, and the reaction solution was concentrated. To the concentrate was added n-hexane (5 ml) to cause crystallization of the reaction product. The resulting product was recovered by filtration and washed with n-hexan and dried. There were thus obtained 34.8 mg of the desired product (34.8 mg).

Fuente