Reacción #95310

Ecuación de reacción

N-(2-cyanoethyl)-3-methylaniline

chloroformic acid-3-(trichloromethylcarbonylamino)-phenyl ester

→

N-(2-cyanoethyl)-3-methylcarbanilic acid-[3-(trichloromethylcarbonylamino)-phenyl]-ester

Disolventes

acetonitrile

—

ice water

acetonitrile

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONis added dropwise
2. 2
   TemperaturaThe reaction mixture is heated
3. 3
   Temperaturacooled
4. 4
   Filtraciónthe precipitate filtered
5. 5
   Otrorecrystallized from isopropanol

Procedimiento

Into a solution of 16.0 g N-(2-cyanoethyl)-3-methylaniline in 100 ml acetonitrile, 31.7 g chloroformic acid-3-(trichloromethylcarbonylamino)-phenyl ester taken up in 100 ml acetonitrile is added dropwise. The reaction mixture is heated to boiling for another 10 minutes, cooled, stirred in 500 ml ice water, the precipitate filtered and recrystallized from isopropanol.

Fuente