Reacción #95250

Ecuación de reacción

2-(5-carboxypentyl)-2-cyclopentenone

p-toluenesulfonic acid

→

2-(5-carbethoxypentyl)-2-cyclopentenone

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe solvent is evaporated
2. 2
   workup.DISSOLUTIONthe residue is dissolved in ether
3. 3
   LavadoThe organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution
4. 4
   Secadodried (MgSO4)
5. 5
   Otroevaporated
6. 6
   Otroto give 1.371 g

Procedimiento

A solution of 1.309 g. (0.00668 mole) of 2-(5-carboxypentyl)-2-cyclopentenone (Example 52) and 90 mg. of p-toluenesulfonic acid in 150 ml. of ethanol is refluxed for 18 hours. The solvent is evaporated and the residue is dissolved in ether. The organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution, dried (MgSO4), and evaporated to give 1.371 g. of a light yellow oil.

Fuente