Reacción #94898

Ecuación de reacción

1-methyldecylamine

3-phenyl-3-(4-nitrophenyl)propenoic acid

ethyl chloroformate

→

title compound

Rendimiento 51.0%

N-(1-Methyldecyl)-3-phenyl-3-(4-nitrophenyl)propenamide

Rendimiento 51.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrosubstantially according to the procedure of Preparation 21
2. 2
   OtroThe solid was recrystallized from hexane
3. 3
   Otrogiving a small amount of material which
4. 4
   OtroThe mother liquors were evaporated in vacuo
5. 5
   Otroto give an oil which
6. 6
   FiltraciónThe solid was filtered off

Procedimiento

The title compound was prepared from 3-phenyl-3-(4-nitrophenyl)propenoic acid via mixed anhydride formation using ethyl chloroformate, followed by reaction with 1-methyldecylamine, substantially according to the procedure of Preparation 21. The product was induced to solidify by trituration under hexane. The solid was recrystallized from hexane, giving a small amount of material which was discarded. The mother liquors were evaporated in vacuo to give an oil which solidified when stirred under acetonitrile. The solid was filtered off, giving a 51% yield of the title compound, m.p. 69°-71° C.

Fuente