Reacción #94896

Ecuación de reacción

decylamine

3-phenyl-3-(4-nitrophenyl)propenoyl chloride

→

N-Decyl-3-phenyl-3-(4-nitrophenyl)propenamide

Disolventes

tetrahydrofuran

tetrahydrofuran

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe solvent was removed by evaporation in vacuo
2. 2
   Otrothe residue was partitioned between ethyl acetate and water
3. 3
   OtroThe layers were separated
4. 4
   Lavadothe ethyl acetate layer was washed with water
5. 5
   Otrodried
6. 6
   Otroevaporated in vacuo

Procedimiento

To a stirred solution of 5.89 g. of decylamine in 25 ml. of tetrahydrofuran was added a solution of 4.89 g. of 3-phenyl-3-(4-nitrophenyl)propenoyl chloride in 25 ml. of tetrahydrofuran, dropwise, during 20 minutes, at ice-bath temperature. The solvent was removed by evaporation in vacuo and the residue was partitioned between ethyl acetate and water. The layers were separated, and the ethyl acetate layer was washed with water, dried using sodium sulfate, and then evaporated in vacuo. This afforded 5.6 g. of the title compound, m.p. 91°-93° C.

Fuente