Reacción #944007

Ecuación de reacción

aniline

4-fluoro-N-(4-methylthiobenzylidene)aniline

trimethylsilyl cyanide

→

title compound

α-(4-Fluoroanilino)-α-(4-methylthiophenyl) acetonitrile

Condiciones de reacción

Procedimiento

Following a procedure similar to that described in Example 1(i), but using 4-methylthiobenzaldehyde and 4-fluoroaniline as starting materials, 4-fluoro-N-(4-methylthiobenzylidene)aniline was obtained in a yield of 89%. This aniline compound and trimethylsilyl cyanide were then reacted together in a similar manner to that described in Example 1(ii), to give the title compound as a slightly yellow powder (yield 47%).

Fuente