Reacción #94331

ord-177c8f38f14b4e4d99132f91365c0976

Ecuación de reacción

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O.O.O.O
ampicillin trihydrate
[Na+].[OH-]
sodium hydroxide
[Na+].[OH-]
NaOH
→
CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)[O-].[Na+]
sodium ampicillin

Reactantes

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O.O.O.O
ampicillin trihydrate
[Na+].[OH-]
sodium hydroxide
[Na+].[OH-]
NaOH

Reactivos

Ninguno

Disolventes

O
water

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

A suspension of 24.18 gm (60 millimols) of ampicillin trihydrate in 140 ml of water was admixed with 55.2 ml of an aqueous 1N sodium hydroxide solution (8% less than equimolar amount of NaOH) in the manner and under the conditions described in Example 1, and the sodium ampicillin was isolated in exactly the same manner as in Example 1.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04130558uspto-grants-1978_12