Reacción #94154

ord-19fd36c6ce144b2cb18c675d32583c2d

Ecuación de reacción

COc1ccc(COC(=O)NCCCC(CSC(C)=O)C(=O)N2CCC[C@H]2C(=O)O)cc1
1-[2-acetylthiomethyl-5-(p-methoxybenzyloxycarbonylamino)pentanoyl]-L-proline
CC(=O)NC(CSC(C)=O)C(=O)N1CCC[C@H]1C(=O)O
N,S-diacetyl-DL-cysteinyl-L-proline
→
COc1ccc(COC(=O)NCCCC(CS)C(=O)N2CCC[C@H]2C(=O)O)cc1
1-[2-mercaptomethyl-5-(p-methoxybenzyloxycarbonylamino)pentanoyl]-L-proline

Reactantes

COc1ccc(COC(=O)NCCCC(CSC(C)=O)C(=O)N2CCC[C@H]2C(=O)O)cc1
1-[2-acetylthiomethyl-5-(p-methoxybenzyloxycarbonylamino)pentanoyl]-L-proline
CC(=O)NC(CSC(C)=O)C(=O)N1CCC[C@H]1C(=O)O
N,S-diacetyl-DL-cysteinyl-L-proline

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

By substituting 1-[2-acetylthiomethyl-5-(p-methoxybenzyloxycarbonylamino)pentanoyl]-L-proline for the N,S-diacetyl-DL-cysteinyl-L-proline in the procedure of Example 5, 1-[2-mercaptomethyl-5-(p-methoxybenzyloxycarbonylamino)pentanoyl]-L-proline is obtained.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04129571uspto-grants-1978_12