Reacción #940155

Ecuación de reacción

391

tert-Butyl 2-(4-(Boc-aminomethyl)benzamido)phenylcarbamate

DCM TFA

→

title compound

Rendimiento 100.0%

4-(Aminomethyl)-N-(2-aminophenyl)benzamide

Rendimiento 100.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   ConcentraciónThe reaction mixture was concentrated in vacuo

Procedimiento

A solution of 391 (840 mg, 1.9 mmol) in 2:1 mixture of DCM/TFA (6 mL) was stirred at room temperature for 2 hours. The reaction mixture was concentrated in vacuo to afford the title compound as a mixture of the mono and di-TFA salt. (1.33 g, 100% yield). LRMS: (calc) 241.2; (found) 242.2 (M+H1).

Fuente