Reacción #939025

ord-234d20701a58422ca6165bef468e4a83

Ecuación de reacción

CCOCCCl
2-chloroethyl ethyl ether
CCc1nc2ccccc2[nH]1
2-ethylbenzimidazole
CCOCCn1c(CC)nc2ccccc21
1-(2-Ethoxyethyl)-2-ethyl-1H-benzimidazole
Rendimiento 80.0%

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

1-(2-Ethoxyethyl)-2-ethyl-1H-benzimidazole was synthesized as in Synthesis Example 1 except that an equimolar amount of 2-ethylbenzimidazole was used instead of benzimidazole, and an equimolar amount of 2-chloroethyl ethyl ether was used instead of 2-chloroethyl methyl ether. Yield 80%.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07252925B2uspto-grants-2007_08