Reacción #939019

Ecuación de reacción

6-decenoic acid

Methyl 6-bromodecanoate

quinoline

methyl 5-decenoate

methyl 6-decenoate

→

5-decenoic acid

Rendimiento 35.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroto react at 240° C. for 5 minutes
2. 2
   Extracciónthe reaction solution was extracted with ether
3. 3
   Lavadowashed with dilute sulfuric acid
4. 4
   Lavadowashed with water
5. 5
   Otrodried
6. 6
   Otroevaporated
7. 7
   Otroto remove the solvent
8. 8
   workup.DISTILLATIONdistilled
9. 9
   Otrogiving

Procedimiento

Methyl 6-bromodecanoate (1.2 g) and quinoline (1.2g) were mixed together, and then allowed to react at 240° C. for 5 minutes. After the reaction was completed, the reaction solution was extracted with ether, washed with dilute sulfuric acid, washed with water, dried, evaporated to remove the solvent, and then distilled, thereby giving a mixture of methyl 5-decenoate and methyl 6-decenoate (310 mg). The mixture was hydrolyzed in a coventional manner, thereby giving a mixture (270 mg) of 5-decenoic acid and 6-decenoic acid (1/1).

Fuente