Reacción #93375

Ecuación de reacción

alpha-isopropyl-alpha-[3-[N-[3-(2-nitrophenoxy)propyl]-N-methylamino]propyl]-3,4,5-trimethoxyphenylacetonitrile

→

desired compound

Rendimiento 105.2%

Alpha-isopropyl-alpha-[3-[N-[3-(2-aminophenoxy)propyl]-N-methylamino]propyl]-3,4,5-trimethoxyphenylacetonitrile

Rendimiento 105.2%

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe catalyst was filtered off
2. 2
   Otrofiltrate was evaporated

Procedimiento

0.92 g of alpha-isopropyl-alpha-[3-[N-[3-(2-nitrophenoxy)propyl]-N-methylamino]propyl]-3,4,5-trimethoxyphenylacetonitrile was hydrogenated in 20 ml of methanol over 10 mg of platinum oxide at atmospheric pressure and room temperature. The catalyst was filtered off and filtrate was evaporated to give 0.91 g of the desired compound as a yellow oil. The oxalate of this compound was obtained in the usual manner.

Fuente