Reacción #93196

Ecuación de reacción

3-(2,2-dibromovinyl)-benzaldehyde

KCN

3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid chloride

→

3-(2,2-Dibromovinyl)-α-cyanobenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate

Disolventes

ether

water

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONthorough mixing
2. 2
   OtroThe phases are separated
3. 3
   Extracciónthe aqueous phase is extracted twice
4. 4
   LavadoThe ether solution is washed with sodium bisulfite, NaHCO3 and water
5. 5
   Secadodried over Na2SO4
6. 6
   Otroevaporated down

Procedimiento

In a two-phase reaction mixture, 6.1 g (0.021 mole) of 3-(2,2-dibromovinyl)-benzaldehyde in 50 ml of ether, 1.5 g (0.023 mole) of KCN in 20 ml of water, 5.0 g (0.022 mole) of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid chloride and 0.5 g of triethylbenzylammonium chloride are stirred at room temperature, and thorough mixing is continued overnight at 25° C. The phases are separated and the aqueous phase is extracted twice by shaking with ether. The ether solution is washed with sodium bisulfite, NaHCO3 and water, dried over Na2SO4 and evaporated down.

Fuente