Reacción #93147

Ecuación de reacción

N-(4-methoxybenzoyl)-piperazine

morpholine

anisic acid chloride

chloroacetic acid morpholide

chloroacetyl chloride

piperazine

→

4-(4-Methoxybenzoyl)-piperazin-1-yl-acetic acid morpholide

Disolventes

acetic acid

toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrowas obtained as a viscous oil
2. 2
   Otrowas obtained as a colourless oil

Procedimiento

The N-(4-methoxybenzoyl)-piperazine used as a starting substance was obtained as a viscous oil by reacting 1 mol of piperazine with 0.5 mol of anisic acid chloride in glacial acetic acid. The chloroacetic acid morpholide used as a starting substance was obtained as a colourless oil by reacting 2 mol of morpholine with 1 mol of chloroacetyl chloride in toluene.

Fuente