Reacción #92973

Ecuación de reacción

p-chlorophenol

1,4-dichloro-2-butanol

sodium hydroxide

→

4-Chloro-1-(4-chlorophenoxy)-2-butanol

Disolventes

water

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrothe procedure of Preparation 7 from 45 g
2. 2
   Otro(36.1%) of product which melted at 62°-64° C. after recrystallization from isopropanol

Procedimiento

4-Chloro-1-(4-chlorophenoxy)-2-butanol was prepared using the procedure of Preparation 7 from 45 g. (0.5 mole) of p-chlorophenol, 72 g. (0.5 mole) of 1,4-dichloro-2-butanol, 40 g. (1.0 mole) of sodium hydroxide and 400 ml. of water to give 85 g. (36.1%) of product which melted at 62°-64° C. after recrystallization from isopropanol.

Fuente