Reacción #92933

Ecuación de reacción

1-bromo-2-(2-methylphenyl)-2-oxoethane

1-methylimidazole

→

1-methyl-3-[2-(2-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide

Rendimiento 34.0%

Disolventes

diethyl ether

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe reaction solvent was decanted
2. 2
   Lavadothe residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONThe residue was dissolved in hot acetonitrile
4. 4
   Temperaturathe resulting solution was cooled
5. 5
   workup.ADDITIONdiluted with diethyl ether
6. 6
   OtroThe solid was collected
7. 7
   Otrorecrystallized twice from acetonitrile/diethyl ether

Procedimiento

A solution of 4.22 g (0.02 mol) of 1-bromo-2-(2-methylphenyl)-2-oxoethane, 2.64 g (0.032 mol) of 1-methylimidazole and 60 ml of diethyl ether was stirred at room temperature for approximately 17 hours. The reaction solvent was decanted and the residue was washed with diethyl ether. The residue was dissolved in hot acetonitrile, and the resulting solution was cooled and diluted with diethyl ether. The solid was collected and recrystallized twice from acetonitrile/diethyl ether to afford 1.99 g of 1-methyl-3-[2-(2-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide as white needles. (34% yield) mp=152°-154° C.

Fuente