Reacción #91323
ord-0bd1d95c328c427793bf4c5df71f66a9
Ecuación de reacción
4-phenoxybenzylamine
3-fluoroisonicotinic acid
→
title compound
Rendimiento 36.0%
3-[(4-phenoxybenzyl)amino]pyridine-4-carboxylic acid
Rendimiento 36.0%
Reactivos
Ninguno
Condiciones de reacción
Condiciones detalladas
See reaction.notes.procedure_details.
Procedimiento
The title compound was prepared in 36% yield from 4-phenoxybenzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. 1H NMR (400 MHz, DMSO-d6): δ 13.42 (br s, 1H), 8.18 (s, 1H), 7.83 (d, 1H, J=5.0 Hz), 7.57 (d, 1H, J=5.0 Hz), 7.35-7.40 (m, 4H), 7.13 (t, 1H, J=7.2), 6.97-7.02 (m, 4H), 4.55 (s, 2H). [M+H] calc'd for C19H16N2O3, 321. found 321.