Reacción #91319
ord-422526b79e104496a27efe39006b929c
Ecuación de reacción
4-phenylbenzylamine
3-fluoroisonicotinic acid
→
title compound
Rendimiento 36.0%
3-[(biphenyl-4-ylmethyl)amino]pyridine-4-carboxylic acid
Rendimiento 36.0%
Reactivos
Ninguno
Condiciones de reacción
Condiciones detalladas
See reaction.notes.procedure_details.
Procedimiento
The title compound was prepared in 36% yield from 4-phenylbenzylamine and 3-fluoroisonicotinic acid according to the procedure for the preparation of Example 3. 1H NMR (400 MHz, DMSO-d6): δ 13.55 (br s, 1H), 8.17 (s, 1H), 7.83 (d, 1H, J=5.0 Hz), 7.71 (m, 4H), 7.58 (d, 1H, J=5.0 Hz), 7.32-7.48 (m, 5H), 4.62 (s, 2H). [M+H] calc'd for C19H16N2O2, 305. found 305.