Reacción #91297

Ecuación de reacción

3-Chloromethyl-2-cyclopentylsulfanyl-6-methyl-pyridine

3-(3-chloro-4-hydroxy-phenyl)-propionic acid ethyl ester

→

title compound

Rendimiento 58.0%

3-[3-chloro-4-(2-cyclopentylsulfanyl-6-methyl-pyridin-3-ylmethoxy)-phenyl]-propionic acid

Rendimiento 58.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroto react sequentially in the same manner as in Steps A and B of Example 1

Procedimiento

3-Chloromethyl-2-cyclopentylsulfanyl-6-methyl-pyridine (35 mg, 0.15 mmol) obtained in Step C of Preparation Example 36 and 3-(3-chloro-4-hydroxy-phenyl)-propionic acid ethyl ester (36 mg, 0.17 mmol) obtained in Step C of Preparation Example 42 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (30 mg, 58%).

Fuente