Reacción #91247

Ecuación de reacción

2-Chloromethyl-6-cyclopentylsulfanyl-pyridine

3-(3-chloro-4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester

→

title compound

Rendimiento 85.0%

3-[3-chloro-4-(6-cyclopentylsulfanyl-pyridin-2-ylmethoxy)-phenyl]-2-methyl-propionic acid

Rendimiento 85.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroto react sequentially in the same manner as in Steps A and B of Example 1

Procedimiento

2-Chloromethyl-6-cyclopentylsulfanyl-pyridine (37 mg, 0.16 mmol) obtained in Step C of Preparation Example 27 and 3-(3-chloro-4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester (43 mg, 0.17 mmol) obtained in Step B of Preparation Example 46 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (51 mg, 85%).

Fuente