Reacción #90987

Ecuación de reacción

(S)-methyl 2-(2-((tert-butoxycarbonyl)amino)-4-methylpentanamido) acetate

(S)-methyl 2-(2-((tert-butoxycarbonyl)amino)-4-methylpentanamido)acetate

HCl

→

(S)-methyl 2-(2-amino-4-methylpentanamido)acetate hydrochloride

Disolventes

1,4-dioxane

1,4-dioxane

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe reaction mixture was filtered

Procedimiento

To a solution of (S)-methyl 2-(2-((tert-butoxycarbonyl)amino)-4-methylpentanamido) acetate (3w) in 1,4-dioxane was added a 5M solution of HCl in 1,4-dioxane at room temperature. The reaction was stirred at room temperature for 16 h. The reaction mixture was filtered to afford (S)-methyl 2-(2-amino-4-methylpentanamido)acetate hydrochloride (4w) as the filtered solid.

Fuente