Reacción #90040

ord-04738769c837440ebf0070169c74bf2b

Ecuación de reacción

CC1(C)c2cc(C(=O)O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound B2-28
CC1(C)c2cc(C(=O)O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-carboxylic acid
OC1CCNCC1
piperidin-4-ol
→
CC1(C)c2cc(C(=O)N3CCC(O)CC3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
title compound
CC1(C)c2cc(C(=O)N3CCC(O)CC3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-(4-Hydroxy-piperidin-1-carbonyl)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

Reactantes

CC1(C)c2cc(C(=O)O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound B2-28
CC1(C)c2cc(C(=O)O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-carboxylic acid
OC1CCNCC1
piperidin-4-ol
—
Compound B3

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Under the same conditions as the method for synthesizing Compound B3-15, the title compound was prepared from Compound B2-28 and piperidin-4-ol.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US09440922B2uspto-grants-2016_09