Reacción #89320

ord-2c3e2a4a70ce44ff85eaf6a7d8e61505

Ecuación de reacción

Cc1ccc(-c2cnccn2)c(C(=O)O)c1
5-methyl-2-(pyrazin-2-yl)benzoic acid
Cc1ccc(Br)nc1
2-bromo-5-methylpyridine
→
Cc1ccc(-c2ccc(C)cc2C(=O)O)nc1
title compound
Cc1ccc(-c2ccc(C)cc2C(=O)O)nc1
5-Methyl-2-(5-methylpyridin-2-yl)benzoic acid

Reactantes

Cc1ccc(-c2cnccn2)c(C(=O)O)c1
5-methyl-2-(pyrazin-2-yl)benzoic acid
Cc1ccc(Br)nc1
2-bromo-5-methylpyridine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The title compound was synthesized following the same general protocol as described for 5-methyl-2-(pyrazin-2-yl)benzoic acid in Example A19, using 2-bromo-5-methylpyridine. ESI-MS (m/z): 228 [M+1]+.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US09440982B2uspto-grants-2016_09