Reacción #88239

ord-03bfa14da0a648559a9d736cfbfbcce9

Ecuación de reacción

NCc1ccc(Cl)c(Cl)c1
(3,4-dichlorophenyl)methanamine
NC(=O)c1cccc2c(O)nnnc12
4-hydroxybenzo[d][1,2,3]-triazine-8-carboxamide
NC(=O)c1cccc2c(NCc3ccc(Cl)c(Cl)c3)nnnc12
title compound
NC(=O)c1cccc2c(NCc3ccc(Cl)c(Cl)c3)nnnc12
4-((3,4-dichlorobenzyl)amino)benzo[d][1,2,3]triazine-8-carboxamide

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroCompound 2 was prepared

Procedimiento

Compound 2 was prepared following general synthetic scheme 7 wherein (3,4-dichlorophenyl)methanamine was reacted with 4-hydroxybenzo[d][1,2,3]-triazine-8-carboxamide to give the title compound. LC-MS [350 (M+1)], 1H NMR (400 MHz, DMSO-d6): δ 9.37 (s, 1H), 9.31 (t, 1H), 8.54 (d, 1H), 8.49 (d, 1H), 8.05 (s, 1H), 8.00 (t, 1H), 7.70 (s, 1H), 7.60 (d, 1H), 7.40 (d, 1H), 4.90 (d, 1H).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US09440968B2uspto-grants-2016_09