Reacción #87268

Ecuación de reacción

N1,N1′-([1,1′-biphenyl]-3,5-diylbis(methylene))bis(N3-(3-(isobutylamino)propyl)propane-1,3-diamine)

N1,N1′-([1,1′-Biphenyl]-3,5-diylbis(methylene))bis(N3-(3-(isobutylamino)propyl)propane-1,3-diamine)

HCl

→

desired product

Rendimiento 89.0%

N1,N1′-([1,1′-Biphenyl]-3,5-diylbis(methylene))bis(N3-(3-(isobutylamino)propyl)propane-1,3-diamine) hydrochloride salt

Rendimiento 89.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe resulting white solid was collected by vacuum filtration
2. 2
   Lavadowashed with minimal MeOH and Et2O

Procedimiento

To the crude N1,N1′-([1,1′-biphenyl]-3,5-diylbis(methylene))bis(N3-(3-(isobutylamino)propyl)propane-1,3-diamine) from step 2 was added methanolic HCl (75 mL, 2.0M). The resulting white solid was collected by vacuum filtration and washed with minimal MeOH and Et2O and stored under high vacuum to afford the desired product (9.3 g, 89%) as a white solid.

Fuente