Reacción #85877

Ecuación de reacción

6-((dibenzylamino)methyl)morpholin-3-one

→

6-(aminomethyl)morpholin-3-one

Disolventes

EtOH

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroequipped under H2 balloon overnight
2. 2
   FiltraciónThe solution was filtered
3. 3
   Concentraciónconcentrated
4. 4
   Otroto give white oil
5. 5
   OtroThe crude product was used directly for next step without purification

Procedimiento

A solution of 6-((dibenzylamino)methyl)morpholin-3-one (340 mg, 1.09 mmol), Pd(OH)2/C (170 mg) in EtOH (30 mL) was stirred equipped under H2 balloon overnight. The solution was filtered and concentrated to give white oil. The crude product was used directly for next step without purification.

Fuente