Reacción #84816

Ecuación de reacción

4-Bromo-2,6-dimethoxyphenol

2-furylboronic acid

→

4-(furan-2-yl)-2,6-dimethoxyphenol

Rendimiento 79.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroused in the synthesis of Example 21
2. 2
   OtroPurification by chromatography (20-40% EtOAc-hexanes)

Procedimiento

4-Bromo-2,6-dimethoxyphenol (Lee, H.; et al. Tetrahedron Letters, 2004, 45, 1019) was coupled with 2-furylboronic acid according to the procedure used in the synthesis of Example 21. Purification by chromatography (20-40% EtOAc-hexanes) gave 4-(furan-2-yl)-2,6-dimethoxyphenol as a light orange solid (1.95 g, 79% yield).

Fuente