Reacción #8442

Ecuación de reacción

acetic anhydride

triethylamine

dimethylaminopyridine

product

bis-α-naphthyl-(4-[2-hydroxy-ethoxy]-2-hydroxy-phenyl)-triazine

→

bis-αnaphthyl-(4-[2-acetoxy-ethoxy]-2-hydroxy-phenyl)-triazine

Disolventes

dichloromethane

Condiciones de reacción

Tratamiento posterior

1. 1
   TemperaturaThe reaction mixture is heated to boiling
2. 2
   Otrothe solvent is removed in vac
3. 3
   LavadoThe organic phase is washed with water
4. 4
   Secadodried with magnesium sulfate
5. 5
   OtroAfter removal of the solvent
6. 6
   Otrothe residue is chromatographed on silica gel
7. 7
   Otroyielding the product

Procedimiento

9.11 g of acetic anhydride, 18.1 g of triethylamine and 0.73 g of dimethylaminopyridine in 400 ml of anhydrous dichloromethane are added to the product from Example A9. The reaction mixture is heated to boiling. When the reaction is complete (monitoring by TLC), the solvent is removed in vac. and the residue is taken up in dichloromethane. The organic phase is washed with water and dried with magnesium sulfate. After removal of the solvent, the residue is chromatographed on silica gel, yielding the product having the following NMR data:

Fuente