Reacción #83634

Ecuación de reacción

2-Fluorobenzaldehyde

malonitrile

→

2-Fluorobenzylidenemalonitrile

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   TemperaturaThe solution was heated
2. 2
   Temperaturato reflux
3. 3
   OtroOnce the vigorous reaction
4. 4
   Temperaturathe solution was heated for 15 minutes
5. 5
   Temperaturachilled
6. 6
   FiltraciónCrystals of product were filtered off
7. 7
   Lavadowashed with ethanol, m.p. 122° C.

Procedimiento

2-Fluorobenzaldehyde (15.8 ml) was dissolved in ethanol (100 ml) and to the stirred solution was added malonitrile (9.9 g). The solution was heated to reflux, the heating discontinued and piperidine (4 drops) was added. Once the vigorous reaction had diminished, the solution was heated for 15 minutes and then chilled. Crystals of product were filtered off and washed with ethanol, m.p. 122° C.

Fuente