Reacción #833563

ord-10fbda7314014fd9af57ee8ed0823066

Ecuación de reacción

CC(C)(C)OC(=O)NN
tert-butyl hydrazinecarboxylate
C=CS(=O)(=O)c1ccccc1
phenylvinylsulphone
→
CC(C)(C)OC(=O)NNCCS(=O)(=O)c1ccccc1
Tert-butyl N′-(2-phenylsulphonyl-ethyl)-hydrazinecarboxylate

Reactantes

CC(C)(C)OC(=O)NN
tert-butyl hydrazinecarboxylate
C=CS(=O)(=O)c1ccccc1
phenylvinylsulphone

Reactivos

Ninguno

Disolventes

CCO
ethanol

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroThen the solvent is removed completely
  2. 2
    Otrothe residue is chromatographed over silica gel (cyclohexane/ethyl acetate)

Procedimiento

A solution of 0.79 g tert-butyl hydrazinecarboxylate and 1.00 g phenylvinylsulphone in 8 ml of ethanol is refluxed for 5 h with stirring. Then the solvent is removed completely and the residue is chromatographed over silica gel (cyclohexane/ethyl acetate).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07393847B2uspto-grants-2008_07