Reacción #833223

Ecuación de reacción

2,6-dichloro-4-nitrobenzaldehyde

Aminoguanidine hydrogen carbonate

hydrochloric acid

→

(2,6-dichloro-4-nitrobenzylidene amino)-guanidine hydrochloride

Disolventes

ethanol

diethyl ether

water

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONwas added
2. 2
   Temperaturathe suspension heated
3. 3
   Temperaturaunder reflux for 2.5 h
4. 4
   TemperaturaThe reaction mixture was cooled

Procedimiento

Aminoguanidine hydrogen carbonate (0.96 g, 7.0 mmol) was added to a solution of concentrated hydrochloric acid (0.6 cm3) in water (2 cm3). After diluting the resulting solution with ethanol (20 cm3), 2,6-dichloro-4-nitrobenzaldehyde (1.53 g, 7.0 mmol) was added and the suspension heated under reflux for 2.5 h. The reaction mixture was cooled and diluted with diethyl ether to yield (2,6-dichloro-4-nitrobenzylidene amino)-guanidine hydrochloride as a yellow solid, mp 190° C. (dec).

Fuente