Reacción #823518

Ecuación de reacción

2-Chloro-benzenesulfonyl chloride

(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(5-amino-pyridin-3-yl)-methanone

N-[5-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-pyridin-3-yl]-3,5-difluoro-benzenesulfonamide

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title compound

N-[5-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-pyridin-3-yl]-2-chloro-benze nesulfonamide

Condiciones de reacción

Procedimiento

The title compound was prepared from 2-Chloro-benzenesulfonyl chloride (19.6 mg, 0.093 mmol) and (4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(5-amino-pyridin-3-yl)-methanone (25 mg, 0.084 mmol) by procedures analogous to those described for the preparation of N-[5-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-pyridin-3-yl]-3,5-difluoro-benzenesulfonamide. MS: 471.2 (MH+); HPLC Rf: 4.71 min. (HPLC method 4).

Fuente