Reacción #792146

Ecuación de reacción

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one

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title compound

Rendimiento 59.6%

1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)propan-1-one

Rendimiento 59.6%

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroto give a yellow solution
2. 2
   FiltraciónThe reaction mixture was filtered
3. 3
   Otroevaporated
4. 4
   Lavadothe solid residue was washed with diethylether
5. 5
   Otrodried

Procedimiento

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one (0.5 g, 1.857 mmol) was added to methanol (50 ml) to give a yellow solution. Palladium on carbon (0.05 g) was added. Product was hydrogenated while stirring till conversion was completed (checked by TLC). The reaction mixture was filtered, evaporated and the solid residue was washed with diethylether, and dried to yield 0.3 g (57%) of the title compound.

Fuente