Reacción #790940

Ecuación de reacción

acetone

4-(chloroacetyloxy)benzene sulfonic acid

sodium

dimethyloctylamine

dimethylacetamide

→

product

4-(dimethyloctylaminoacetoxy) benzene sulfonic acid

Condiciones de reacción

Tratamiento posterior

1. 1
   Filtraciónfiltered
2. 2
   Lavadowashed twice with 250 mL potions of acetone
3. 3
   Otrodried at 50°-60° C. under reduced pressure

Procedimiento

To a stirred slurry of 54.5 g (0.2 mole) of 4-(chloroacetyloxy)benzene sulfonic acid, a sodium salt, in 250 mL of dimethylacetamide was added dropwise over 15 minutes 31.5 g (0.2 mole) of dimethyloctylamine. After stirring for an additional 3 hours, the contents of the flask became a solid mass. This was slurried with 200 mL of acetone, filtered, washed twice with 250 mL potions of acetone and dried at 50°-60° C. under reduced pressure to give 74 g of product. 1H NMR (DMSO-d6) δ0.9 (t, 3H), 1.24 (m, 10H), 1.6 (m, 2H), 3.3 (s, 6H), 3.5 (m 2H), 4.95 (s, 2H), 7.1 (d, 2H), 7.7 (d, 2H).

Fuente