Reacción #790608

Ecuación de reacción

fumarate

(R)-3-aminoquinuclidine

2-methoxybenzoyl isocyanate

→

(R)-N-[[[1-Azabicyclo[2.2.2]octan-3-yl] amino]carbonyl]-2-methoxybenzamide

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe above compound was prepared

Procedimiento

The above compound was prepared, following the procedure of Example 1, from (R)-3-aminoquinuclidine (0.63 g, 5 mmol) and 2-methoxybenzoyl isocyanate (1.33 g, 7.5 mmol). The product (1.49 g) was converted to the 1:1 fumarate, mp 158°-159° C. (dec).

Fuente