Reacción #790599

Ecuación de reacción

succinate

3-aminoquinuclidine

2-fluorobenzoyl isocyanate

→

N-[[[1-Azabicyclo[2.2.2]octan-3-yl]amino]carbonyl]-2-fluorobenzamide

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe above compound was prepared

Procedimiento

The above compound was prepared, following the procedure of Example 1, from 3-aminoquinuclidine (0.63 g, 5 mmol) and crude 2-fluorobenzoyl isocyanate (1.3 g, ca 7 mmol). The product (1.35 g) was converted to the 1:1 succinate, mp 187°-188° C.

Fuente